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Dosage Form: Ear drops [P] 1 %
Recommended Dose: 4-6 drops in the affected ear every 2-3
hours.
Indications: Treatment of external otitis and prevention
of Swimmer’s Ear.
Dosage Form: Nasal spray 50 mcg/dose (££,I)
Recommended Dose: Nasal inhalation: One puff into each
nostril three times daily with a maximum of: 20 puffs daily for adults and 10
puffs daily for paediatrics. Oral inhalation: Adult: 2 puffs, 3-4 times a day. Severe
case: Initial dose may be doubled. On improvement, dosage adjusted according to
response. Child: 1-2 puffs, 3-4 times a day.
Indications: Allergic rhinitis, vasomotor rhinitis, nasal
polyps, bronchial asthma, chronic obstructive bronchitis.
Contra-Indications: Untreated nasal infection,
haemorrhagic-diathesis or history of recurrent nasal bleeding. Hypersensitivity
to beclomethasone and first trimester of pregnancy.
Special Precautions: If infection of respiratory tract, nassal
passages or paranasal sinuses occurs during treatment, antibacterial therapy
should be promptly instituted.
BENZOIN, STORAX MENTHOL WITH EUCALYPTUS OIL
INHALATION [Tincture Benzoin Co]
Dosage Form: Tincture for inhalation (£,II)
Recommended Dose: As directed for local use.
Indications: As an inhalation in brochitis and acute
laryngitis.
Dosage Form: Ear drop 5% (II)
Recommended Dose: 2-3 drops tds-qid.
Indications: Bacterial infection in otitis externa.
Special Precautions: Caution in presence of perforations of the
tympanic membrane. Avoid prolonged use.
Dosage Form: Nasal drops 0.1 mg/ml (S/R); Nasal spray 10
mcg/metered spray (££,I)
Recommended Dose: 10-20 mcg daily or bd. Child: 5-10 mcg daily
or bd. To be instilled intranasally using a graduated plastic tube filled from
a bottle.
Indications: Diagnosis and treatment of cranial diabetes
insipidus.
Special Precautions: Should not be administered to dehydrated or
overhydrated patients until water balance is adequately restored; in presence
of nasal infection or rhinorrhoea.
Dosage Form: Nasal drops [P] 0.5% (£,II)
Recommended Dose: 2 drops tds. Max use for 1 week.
Indications: Nasal decongestion.
Special Precautions: Avoid excessive use, caution in infants
under 3 months.
Dosage Form: Nasal spray 1% (£££,I)
Recommended Dose: With nasal adapter: 4 metered doses in each
nostril 4 times a day. With oral adapter: 4 metered doses 4 times a day. Child
above 2 yrs: according to age.
Indications: Rhinitis, rhinopharyngitis, sinusitis, sore
throat, tonsilitis, bronchitis, respiratory complications of influenza and pre
and post instrumental investigations.
Special Precautions: Asthma.
Dosage Form: Ear drops 5 vol. (£,II)
Recommended Dose: 1-2 drops to be instilled as required.
Indications: For removal of ear wax.
Dosage Form: Ear drops [P] 10% (£,II)
Recommended Dose: 2-3 drops tds-qid.
Indications: For inflammatory conditions of the external
ear.
Dosage Form: Nasal spray 50 mcg/spray (I*) ORL
Recommended Dose: For treating seasonal and perennial allergic
rhinitis, usual dose is 2 sprays in each nostril once daily. If used for
seasonal allergic rhinitis, initiation of treatment 2 to 4 weeks before
exposure to the allergen is recommended. Symptom improvement occurs 1-2 days
after starting treatment, and maximum benefit occurs within 1-2 weeks.
Indications: Treatment of seasonal and perennial allergic
rhinitis.
Contra-Indications: Hypersensitivity to mometasone.
Special Precautions: a) May cause hypothalamic-pituitary-adrenal
axis suppression, Cushing’s Syndrome, hyperglycemic or glycosuria, especially
in patients with liver failure. b) Children are more susceptible to systemic absorption
and toxicity. c) Discontinue if local irritation develops. d) Avoid use in
uncontrolled infection. e) Avoid contact with eyes and surrounding areas. f)
After prolong use of systemic corticosteroids, switching to nasal mometasone
may result in signs of adrenal insufficiency. g) Mometasone may increase the
risk of serious or fatal infection in individuals exposed to viral illness such
as chicken pox or measles. h) May cause nasal Candida infections. k) Ocular
herpes simplex. l) May cause glaucoma or cataracts. m) Avoid until wound heals
after nasal surgery, nasal trauma, or nasal ulcers. n) Active or quiescent
tuberculosis. o) Untreated fungal, bacterial, systemic viral infections.
Dosage Form: Ear Drops 0.3% (3 mg/ml)
Recommended Dose: For the treatment of otitis externa: Child: Five drops (0.25 mL, 0.75 mg
ofloxacin) instilled into the affected ear twice daily for ten days. Adult: Ten
drops (0.5 mL, 1.5 mg ofloxacin) instilled into the affected ear twice daily
for ten days. Acute Otitis Media in Pediatric with Tympanostomy Tubes: Five
drops (0.25 mL, 0.75 mg ofloxacin) instilled into the affected ear twice daily
for ten days. Chronic
Suppurative Otitis Media with Perforated Tympanic Membranes: Adult: Ten drops
(0.5 mL, 1.5 mg ofloxacin) instilled into the affected ear twice daily for
fourteen days.
Indications: Otitis Externa due to Staphylococcus
aureus and Pseudomonas aeruginosa, Chronic Suppurative Otitis Media
with perforated tympanic membranes due to Staphylococcus aureus, Proteus
mirabilis, and Pseudomonas aeruginosa. Acute Otitis Media with tympanostomy
tubes due to Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus
influenzae, Moraxella catarrhalis, and Pseudomonas
aeruginosa .
Contra-Indications: History of hypersensitivity to ofloxacin,
to other quinolones, or to any of the components in this medication.
Special Precautions: If the infection is not improved after one
week, cultures should be obtained to guide further treatment. If otorrhea
persists after a full course of therapy, or if two or more episodes of otorrhea
occur within six months, further evaluation is recommended to exclude an
underlying condition such as cholesteatoma, foreign body, or a tumor.
Dosage Form: Nasal drops: Adult 0.05%, Paediatric 0.025%,
Nasal spray: 0.05% (££,I)
Recommended Dose: 1-3 drops, 2-3 times daily in each nostril.
Spray bd in each nostril.
Indications: Nasal decongestant in acute rhinitis,
sinusitis, nasopharingitis, Eustachian salpingitis.
Contra-Indications: Hypersensitivity to oxymethazoline.
Special Precautions: Avoid prolonged use; caution in patients
with hypertension, cardiac disease.
POLYMYXIN B SULPHATE + NEOMYCIN SULPHATE +
HYDROCORTISONE
Dosage Form: Ear drops 10, 000 u + 3, 400 u + 10 mg (Otosporine) (££,II)
Recommended Dose: 3 drops instilled into affected ear
tds-qid. External auditory meatus and canal to be thoroughly cleaned and dried
before each application but soap should not be used as the antibiotics may be
inactivated by it.
Indications: Treatment of bacterial infection and
inflammation of the external auditory meatus.
Special Precautions: Should not be used if the ear drum is
perforated, avoid prolonged use.
Dosage Form: Ear drops [P] 5% (£,II)
Recommended Dose: 2-3 drops tds-qid.
Indications: For removal of ear wax.
TRIAMCINOLONE ACETONIDE + NEOMYCIN
+ GRAMICIDIN + NYSTATIN
Dosage Form: Ear drops (Kenacomb) 0.1% + 0.25% +
0.025% +100,000 Units / gram
(££,I)
Recommended Dose: 2-3 drops tds-qid.
Indications: Treatment of bacterial infection and
inflammation of the external auditory meatus.
Special Precautions: Should not be used if the ear drum is
perforated. Avoid prolonged use.
TRIPOLIDINE HYDROCHLORIDE WITH PSEUDOEPHEDRINE HYDROCHLORIDE
Dosage Form: Tablet 2.5 mg/60 mg (¢¢,II), Syrup 1.2 mg/30
mg in 5 ml (££,II)
Recommended Dose: Adults (over 12 years) 1 tablet or 10 ml
every 4-6 hrs. Child: every 4-6 hrs. Infants up to 12 months: 2.5 ml. 1-5 yrs:
5 ml. 6-12 yrs: 5-7.5 ml.
Indications: Nasal and respiratory congestion, common
cold, acute sinusitis, allergic rhinitis and other allergic conditions.
Contra-Indications: Concurrent treatment with MAO inhibitors and
within 2 weeks of stopping treatment.
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